See also these computer simulations in pharmacology and physiology.
#Calcusyn software pdf#
Price: Single user license: US$300/£175 5 user license: US$900/£525 10 user license: US$1500/£875 (all include a manual as pdf file) An additional charge of US$90/£50 is made for supply of a hard copy (CD) if required. Orders outside the United Kingdom, please click here. A screenshot and a downloadable demo are available here. This program can be ordered online. CalcuSyn is suitable for the study of drug mixtures.Ĭomments & References: Suitable for academic labs and pharmaceutical companies. These give a thorough account of the theoretical basis of the analysis methods including the statistical treatment of results.
#Calcusyn software software#
A comprehensive manual is supplied with the software and there is a detailed Help file. The plots drawn by CalcuSyn include dose-effect, median-effect, isobolograms and CI-effect. All data and results are easily accessible by mouse-click on the contents tree. CalcuSyn Version 2.0 has Undo and Redo tools. There are flexible arrangements for printing of results and graphs and their export to spreadsheets, wordprocessors, and graphics packages. CalcuSyn automatically graphs the data and produces reports giving summary statistics on all drugs plus detailed analysis of drug interactions including the Combination Index and EDx (for any value of x). Estimates of accuracy of EDx and CI can be calculated with Monte Carlo simulations or by a highly accurate algebraic estimation algorithm. Data can be processed both for individual drugs, and for constant-ratio or non-constant-ratio combinations of drugs. When the grid is used, data can be processed through wizards which make the software easily accessible to new users. Data can be entered via the keyboard or file import either into the grid or directly into the analysis engine. 4, 450-454). CalcuSyn can easily be integrated with other software. qRT-PCR of GLI1 in A673 (G) and ATRT-03 (H) cells treated with THZ1 and JQ1 individually or in combination at indicated concentrations for 8 h. A CI value of less than 1 indicates synergy. CalcuSyn performs multiple drug dose-effect calculations using the Median Effect methods described by T-C Chou and P. CI value of each drug combination condition was calculated using CalcuSyn software and presented on the bottom. Please bear in mind that the use of the software might be restricted in terms of.
Each download we provide is subject to periodical scanning, but we strongly recommend you to check the package for viruses on your side before running the installation.
CalcuSyn Version 2.0 is the analyzer of combined drug effects, able automatically to quantify phenomena such as synergism and inhibition. The use of combined drug treatments is becoming common in the treatment of cancer and AIDS. Thank you for downloading CalcuSyn from our software portal.